Accelerated stability test for chitosan microspheres

Chitosan is natural biodegradable polymer and highly mucoadhesion properties which are used to enhance the residence time of drug particles in the nasal cavity, until now the detail of degradation of chitosan microspheres have not been studied in detail. For this purpose four formulation of ropinirole loaded chitosan microspheres were prepared using Mini B-290 Buchi spray dryer in various drug to polymer ratio.

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